Alzheimer's & Dementia Clinical Trials

Join groundbreaking research for Alzheimer's disease and related dementias. Access innovative treatments targeting the root causes of cognitive decline.

6,300+ Active StudiesAll Stages WelcomePrevention & Treatment

Promising Treatment Approaches in Trials

FDA Approved

Anti-Amyloid Antibodies

Monoclonal antibodies clearing amyloid plaques, slowing cognitive decline by 27-35% in early-stage patients

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Phase III

Tau Protein Inhibitors

Targeting tau tangles to prevent neuronal damage and preserve memory function

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Phase II/III

GLP-1 Receptor Agonists

Diabetes drugs showing neuroprotective effects and cognitive improvement

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Innovative

Gene Therapy

APOE gene modification and viral vector delivery of protective proteins

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Multi-target

Combination Therapies

Dual-action drugs targeting multiple pathways simultaneously

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Lifestyle

Non-Drug Interventions

Exercise, diet, cognitive training, and multimodal lifestyle approaches

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Prevention & Early Detection Studies

🧬 Genetic Risk Studies

Studies for individuals with APOE4 genes or family history of Alzheimer's, testing preventive treatments before symptoms appear.

  • AHEAD Study - Pre-symptomatic treatment
  • Generation Studies - APOE4 carriers
  • DIAN-TU - Dominantly inherited Alzheimer's
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🔬 Biomarker Studies

Developing blood tests and brain scans to detect Alzheimer's 10-20 years before symptoms, enabling earlier intervention.

  • Blood-based biomarkers (p-tau, Aβ42/40)
  • Advanced PET imaging techniques
  • Digital biomarkers & cognitive testing
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Studies for Patients & Caregivers

👥

Caregiver Support Studies

Research on interventions to reduce caregiver stress and improve quality of life

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💡

Cognitive Enhancement

Brain training, stimulation devices, and cognitive rehabilitation programs

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😌

Behavioral Symptoms

Treatments for agitation, sleep problems, and neuropsychiatric symptoms

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Clinical Trial Participant Story

"When I was diagnosed with mild cognitive impairment, I felt hopeless. Joining an anti-amyloid antibody trial changed everything. Two years later, my cognitive tests have stabilized, and I'm still living independently. Clinical trials gave me hope and potentially years of quality life."

- Robert K., Age 72, Trial Participant

Join the Fight Against Alzheimer's Disease

Every clinical trial participant brings us closer to a cure. Whether you're at risk, newly diagnosed, or caring for someone with Alzheimer's, there's a study for you.